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Unwanted Events and Side Effects in Cognitive Behavior Therapy

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Abstract

Side effects (SEs) are negative reactions to an appropriately delivered treatment, which must be discriminated from unwanted events (UEs) or consequences of inadequate treatment. One hundred CBT therapists were interviewed for UEs and SEs in one of their current outpatients. Therapists reported 372 UEs in 98 patients and SEs in 43 patients. Most frequent were "negative wellbeing/distress" (27% of patients), "worsening of symptoms" (9%), "strains in family relations" (6%); 21% of patients suffered from severe or very severe and 5% from persistent SEs. SEs are unavoidable and frequent also in well-delivered CBT. They include both symptoms and the impairment of social life. Knowledge about the side effect profile can improve early recognition of SEs, safeguard patients, and enhance therapy outcome.

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Notes

  1. The interview is available from michael.linden@charite.de.

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Acknowledgements

The authors thank the Institute for Behavior Therapy Berlin, the Centre for Psychotherapy at the Humboldt-University Berlin and the Institute for Behavior Therapy Brandenburg for participating in the study. We would also like to acknowledge the editorial assistance of Jon Kilner, MS, MA (Pittsburgh, PA).

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Correspondence to Michael Linden.

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Marie-Luise Schermuly-Haupt, Michael Linden and A. John Rush declare that they have no conflict of interest.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

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Informed consent was obtained from all individual participants included in the study.

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Schermuly-Haupt, ML., Linden, M. & Rush, A.J. Unwanted Events and Side Effects in Cognitive Behavior Therapy. Cogn Ther Res 42, 219–229 (2018). https://doi.org/10.1007/s10608-018-9904-y

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